Immunity Evaluation of Inactivated Newcastle Disease Virus Vaccine Inoculated at Different Doses in Day-old Specific-Pathogen-Free Chicks

This research aims to evaluate the immunogenicity of different doses HIPRAVIAR® BPL2 inactivated Newcastle disease virus (NDV) LaSota vaccine. Specific-pathogen-free day-old chicks were divided into 3 groups, and each group was vaccinated subcutaneously with vaccine dose 0.1, 0.2, 0.5 ml, respectively. Blood samples collected measure NDV-specific antibody titers using a hemagglutination inhibition (HI) test enzyme-linked immunosorbent assay (ELISA). The HI result showed that birds ml an increased statistically significant titer compared other doses. Similarly, ELISA corroborated finding. No difference between results detected when measured two kits, Biocheck CK116, CIVTEST® AVI NDV. percentage antibody-positive based on amongst days post-vaccination all positive from 28 42 following vaccination (group D), whereas highest positivity 80% 70% at 0.1 B) 0.2 C), In conclusion, besides in seroconversion, used had important levels seroconversion positivity.